Award Abstract # 2311338
A statistical framework for the analysis of the evolution in shape and topological structure of random objects

NSF Org: DMS
Division Of Mathematical Sciences
Recipient: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Initial Amendment Date: June 14, 2023
Latest Amendment Date: June 14, 2023
Award Number: 2311338
Award Instrument: Standard Grant
Program Manager: Yong Zeng
yzeng@nsf.gov
 (703)292-7299
DMS
 Division Of Mathematical Sciences
MPS
 Directorate for Mathematical and Physical Sciences
Start Date: July 1, 2023
End Date: June 30, 2026 (Estimated)
Total Intended Award Amount: $329,639.00
Total Awarded Amount to Date: $329,639.00
Funds Obligated to Date: FY 2023 = $329,639.00
History of Investigator:
  • Anne van Delft (Principal Investigator)
    av2972@columbia.edu
  • Andrew Blumberg (Co-Principal Investigator)
Recipient Sponsored Research Office: Columbia University
615 W 131ST ST
NEW YORK
NY  US  10027-7922
(212)854-6851
Sponsor Congressional District: 13
Primary Place of Performance: Columbia University
202 LOW LIBRARY 535 W 116 ST MC 4309,
NEW YORK
NY  US  10027
Primary Place of Performance
Congressional District:
13
Unique Entity Identifier (UEI): F4N1QNPB95M4
Parent UEI:
NSF Program(s): TOPOLOGY,
STATISTICS
Primary Program Source: 01002324DB NSF RESEARCH & RELATED ACTIVIT
Program Reference Code(s): 068Z, 079Z
Program Element Code(s): 126700, 126900
Award Agency Code: 4900
Fund Agency Code: 4900
Assistance Listing Number(s): 47.049

ABSTRACT

Modern data sets often consist of sequential collections of point clouds that are samples from underlying objects with intrinsic geometry, such as curves, surfaces, or manifolds. Analyzing the dynamics of these time series of random objects requires qualitative inference methods that capture information on the geometric properties, i.e., the evolution of descriptors of the 'shape.' Analyzing shape is of paramount interest in many research areas such as genomics, climatology, neuroscience, and finance. In this project, we develop novel methodology and provide probabilistic and statistical foundations to model, analyze, and predict the evolution over time of geometric and topological features of data sets. The research will broaden the scope of the methodological interface between mathematics, computer science, statistics, and probability theory and will have direct applications to genomics and cell biology. We focus our theoretical work to support applications coming from two areas in genomics; cell differentiation in development and tumor evolution. This will be done in collaboration with the Herbert and Florence Irving Institute for cancer dynamics (IICD) at Columbia University. The research findings are also expected to influence model-building and data analysis techniques in geospatial data. Besides the theoretical contribution, we will provide software packages to make the inference methods available to a broad audience. The PIs further propose to design classes and produce expository notes from a cross-disciplinary perspective, and provide projects at the interface of mathematical statistics and topological data analysis for summer undergraduate mentoring.

Over the past few decades, there has been substantial interest in the area of geometric data analysis known as topological data analysis (TDA); this provides qualitative multiscale shape descriptors for point clouds. However, in order to draw reliable qualitative inferences on shape and topological features, it is crucial to account for the (evolving) spatial and temporal dependence present in the data. To address these questions, we take the point of view that the fundamental datum is a function, i.e., the observations are points in a function space. This perspective integrates statistical methodology and TDA in the context of functional time series (FTS). We provide novel methodology to model, analyze and predict data generated from nonstationary metric space-valued stochastic processes. Our framework establishes the statistical and probabilistic foundations for applying multiscale geometric descriptors to meaningfully capture their evolving geometric features as well as the investigation of topological invariants. This new methodology will allow practitioners to perform statistical inference to address important scientific questions.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

Please report errors in award information by writing to: awardsearch@nsf.gov.

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