Award Abstract # 1944602
CAREER: Body-Wire: Transforming Healthcare using Secure Human Body Connected Intelligent Nodes

NSF Org: ECCS
Division of Electrical, Communications and Cyber Systems
Recipient: PURDUE UNIVERSITY
Initial Amendment Date: January 21, 2020
Latest Amendment Date: September 13, 2024
Award Number: 1944602
Award Instrument: Continuing Grant
Program Manager: Ale Lukaszew
rlukasze@nsf.gov
 (703)292-8103
ECCS
 Division of Electrical, Communications and Cyber Systems
ENG
 Directorate for Engineering
Start Date: March 15, 2020
End Date: February 28, 2025 (Estimated)
Total Intended Award Amount: $500,000.00
Total Awarded Amount to Date: $500,000.00
Funds Obligated to Date: FY 2020 = $70,178.00
FY 2021 = $105,524.00

FY 2022 = $103,556.00

FY 2023 = $109,377.00

FY 2024 = $111,365.00
History of Investigator:
  • Shreyas Sen (Principal Investigator)
Recipient Sponsored Research Office: Purdue University
2550 NORTHWESTERN AVE # 1100
WEST LAFAYETTE
IN  US  47906-1332
(765)494-1055
Sponsor Congressional District: 04
Primary Place of Performance: Purdue University
155 S. Grant Street
West Lafayette
IN  US  47907-2114
Primary Place of Performance
Congressional District:
04
Unique Entity Identifier (UEI): YRXVL4JYCEF5
Parent UEI: YRXVL4JYCEF5
NSF Program(s): CSR-Computer Systems Research,
Networking Technology and Syst,
CCSS-Comms Circuits & Sens Sys
Primary Program Source: 01002021DB NSF RESEARCH & RELATED ACTIVIT
01002122DB NSF RESEARCH & RELATED ACTIVIT

01002223DB NSF RESEARCH & RELATED ACTIVIT

01002324DB NSF RESEARCH & RELATED ACTIVIT

01002425DB NSF RESEARCH & RELATED ACTIVIT
Program Reference Code(s): 096E, 1045, 105E
Program Element Code(s): 735400, 736300, 756400
Award Agency Code: 4900
Fund Agency Code: 4900
Assistance Listing Number(s): 47.041, 47.070

ABSTRACT

Continually rising cost of healthcare and side-effects of drugs, such as opioid addiction, could be reduced through remote health monitoring systems and closed-loop electroceuticals, which rely on large amount of data continuously traveling around human body from low-energy wearable and implantable sensors to an on-body hub then to the cloud. Today's standard technologies rely on electromagnetic wave for communication around the human body, which is not physically secure and consume orders of magnitude more power than needed by a typical sensor node, making the communication link the energy bottleneck for ultra-low-power body sensor nodes. This research project will lead to a fundamentally new way of thinking about using human body as a "wire" to achieve orders of magnitude lower energy used for communication around the human body while being physically secure (i.e., signals cannot be snooped without physical contact). In addition, this project will use edge-analytics to reduce data volume for efficient Human-Intranet smart sensor nodes. The project will develop the fundamental understanding for designing the smallest (less than one cubic millimeter) body-connected node for connected healthcare. With simulation tools and hardware verification, backed by concrete mathematical model development, this work will open new research directions in Human-Intranet for Healthcare, Human-Computer Interaction and Brain-Machine Interfaces. The outcome of this research will be integrated with undergraduate and graduate courses on Digital Design and Mixed-Signal Design. Mathematical models representing circuit/system level information and energy trade-off will be disseminated through research website. Such experimentally verified models are expected to provide significant impact by serving a broad community of students, researchers, and engineers. Educational prototypes of the research will be used to engage students in educational workshops. The strong engagement through undergraduate research mentorship and minority student mentorship will strengthen the interest of science and technology from underrepresented students.

The objective of this research is to transform data communication around the human body by using the human body as a wire to achieve orders of magnitude reduction in communication energy in the body area network and combining it with in-sensor analytics to reduce data volume without significant reduction in information to further improve energy/information efficiency. The project will develop the foundations of energy-efficient and physically secured network of energy-sparse sensor nodes for Human-Intranet. The research exploits the low-loss human body channel itself to power the sensor, perform edge-analytics to compress the data and extract information before transferring the compressed data using the same low-loss human body channel. The body-wire research is expected to solve the problem of high data traffic by achieving >1000x reduction in energy/information, allowing longer-lasting, smarter, smaller (new form-factors, better patient compliance), and lower cost healthcare. The energy reduction and improved physical security (in addition to encryption) will open possibilities of many new sensor nodes with new form factors (e.g., connected patch) for human-centered healthcare networks. Along with developing bio-physical circuit models for human body as a communication medium, optimized transceiver circuits and systems for lossy broadband electro-quasistatic human body channel will be developed and demonstrated through integrated circuit fabrication and measurement. A system-on-chip with sensing, in-sensor analytics, and human-body-communication transceiver will be designed, fabricated, and measured to demonstrate the end-to-end improvement in energy/information efficiency. The project will develop mathematical models verified by experiments for future design space exploration and information/energy analysis for Human-Intranet. If successful, the project will develop the fundamental understanding of designing the smallest body-connected node for connected healthcare.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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(Showing: 1 - 10 of 25)
Avlani, Shitij and Seo, Dong-Hyun and Chatterjee, Baibhab and Sen, Shreyas "EICO: Energy-Harvesting Long-Range Environmental Sensor Nodes With Energy-Information Dynamic Co-Optimization" IEEE Internet of Things Journal , v.9 , 2022 https://doi.org/10.1109/JIOT.2022.3178422 Citation Details
Chatterjee, Baibhab and Datta, Arunashish and Nath, Mayukh and K, Gaurav Kumar and Modak, Nirmoy and Sen, Shreyas "A 65nm 63.3µW 15Mbps Transceiver with Switched-Capacitor Adiabatic Signaling and Combinatorial-Pulse-Position Modulation for Body-Worn Video-Sensing AR Nodes" 2022 IEEE International Solid- State Circuits Conference (ISSCC) , 2022 https://doi.org/10.1109/ISSCC42614.2022.9731793 Citation Details
Chatterjee, Baibhab and K, Gaurav Kumar and Nath, Mayukh and Xiao, Shulan and Modak, Nirmoy and Das, Debayan and Krishna, Jayant and Sen, Shreyas "A 1.15W 5.54mm 3 Implant with a Bidirectional Neural Sensor and Stimulator SoC utilizing Bi-Phasic Quasi-static Brain Communication achieving 6kbps-10Mbps Uplink with Compressive Sensing and RO-PUF based Collision Avoidance" 2021 Symposium on VLSI Circuits , 2021 https://doi.org/10.23919/VLSICircuits52068.2021.9492445 Citation Details
Chatterjee, Baibhab and Kumar, K Gaurav and Xiao, Shulan and Barik, Gourab and Jayant, Krishna and Sen, Shreyas "A $1.8\mu\mathrm{W}\ 5.5$ mm 3 ADC-less Neural Implant SoC utilizing 13.2pJ/Sample Time-domain Bi-phasic Quasi-static Brain Communication with Direct Analog to Time Conversion" ESSCIRC 2022- IEEE 48th European Solid State Circuits Conference (ESSCIRC) , 2022 https://doi.org/10.1109/ESSCIRC55480.2022.9911420 Citation Details
Chatterjee, Baibhab and Mohseni, Pedram and Sen, Shreyas "Bioelectronic Sensor Nodes for the Internet of Bodies" Annual Review of Biomedical Engineering , v.25 , 2023 https://doi.org/10.1146/annurev-bioeng-110220-112448 Citation Details
Chatterjee, Baibhab and Nath, Mayukh and Kumar_K, Gaurav and Xiao, Shulan and Jayant, Krishna and Sen, Shreyas "Biphasic quasistatic brain communication for energy-efficient wireless neural implants" Nature Electronics , v.6 , 2023 https://doi.org/10.1038/s41928-023-01000-3 Citation Details
Chatterjee, Baibhab and Sen, Shreyas "A 41.5 pJ/b, 2.4GHz Digital-Friendly Orthogonally Tunable Transceiver SoC with 3-decades of Energy-Performance Scalability" IEEE Custom Integrated Circuits Conference (CICC) , v.March , 2020 https://doi.org/10.1109/CICC48029.2020.9075915 Citation Details
Chatterjee, Baibhab and Sen, Shreyas "Energy-Efficient Deep Neural Networks with Mixed-Signal Neurons and Dense-Local and Sparse-Global Connectivity" Asia and South Pacific Design Automation Conference , 2021 https://doi.org/10.1145/3394885.3431614 Citation Details
Datta, Arunashish and Kaur, Upinder and Malacco, Victor and Nath, Mayukh and Chatterjee, Baibhab and Donkin, Shawn S. and Voyles, Richard M. and Sen, Shreyas "In-body to Out-of-body Communication Channel Modeling for Ruminant Animals for Smart Animal Agriculture" 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) , 2021 https://doi.org/10.1109/EMBC46164.2021.9629743 Citation Details
Datta, Arunashish and Kaur, Upinder and Malacco, Victor and Nath, Mayukh and Chatterjee, Baibhab and Donkin, Shawn S. and Voyles, Richard M. and Sen, Shreyas "Sub-GHz In-Body to Out-of-Body Communication Channel Modeling for Ruminant Animals for Smart Animal Agriculture" IEEE Transactions on Biomedical Engineering , 2022 https://doi.org/10.1109/TBME.2022.3213262 Citation Details
Datta, Arunashish and Nath, Mayukh and Chatterjee, Baibhab and Maity, Shovan and Sen, Shreyas "A Quantitative Analysis of Physical Security and Path Loss With Frequency for IBOB Channel" IEEE Microwave and Wireless Components Letters , v.32 , 2022 https://doi.org/10.1109/LMWC.2022.3163077 Citation Details
(Showing: 1 - 10 of 25)

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