
NSF Org: |
CHE Division Of Chemistry |
Recipient: |
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Initial Amendment Date: | December 5, 2009 |
Latest Amendment Date: | June 8, 2015 |
Award Number: | 0938158 |
Award Instrument: | Cooperative Agreement |
Program Manager: |
Colby Foss
cfoss@nsf.gov (703)292-5327 CHE Division Of Chemistry MPS Directorate for Mathematical and Physical Sciences |
Start Date: | December 1, 2009 |
End Date: | September 30, 2015 (Estimated) |
Total Intended Award Amount: | $0.00 |
Total Awarded Amount to Date: | $0.00 |
Funds Obligated to Date: |
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History of Investigator: |
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Recipient Sponsored Research Office: |
874 TRADITIONS WAY TALLAHASSEE FL US 32306-0001 (850)644-5260 |
Sponsor Congressional District: |
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Primary Place of Performance: |
874 TRADITIONS WAY TALLAHASSEE FL US 32306-0001 |
Primary Place of
Performance Congressional District: |
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Unique Entity Identifier (UEI): |
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Parent UEI: |
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NSF Program(s): | Chemical Instrumentation |
Primary Program Source: |
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Program Reference Code(s): |
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Program Element Code(s): |
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Award Agency Code: | 4900 |
Fund Agency Code: | 4900 |
Assistance Listing Number(s): | 47.049 |
ABSTRACT
DMR-0938158
PIs: Boebinger, Marshall
This award will fund the design, construction, and optimization of performance of a 21 Tesla ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometer(FTICR-MS). The rationale for this project draws from the workshop, "Science Challenges and Design Concepts for the Next-Generation High-Performance FT-ICR Mass Spectrometer," organized jointly by National High Magnetic Field Laboratory (NHMFL) and the Environmental Molecular Scienes Laboratory (EMSL), and held on 16-17 January, 2008 at NHMFL. Feasibility of the magnet design has been demonstrated by NHMFL's Magnet Science and Technology group, and three vendors have offered to build it. The other components of the spectrometer will be designed and built by NHMFL permanent staff and two postdoctoral researchers. Ion optics design will be guided by large-scale supercomputer simulations (modeling the interaction of more than 1,000,000 ions). This project will improve every aspect of technical performance: sample introduction, ion source(s), ion transmission, ion external accumulation, ion cyclotron resonance (ICR) excitation and detection, computerized and automated instrument control, higher magnetic field, and data reduction. Magnet delivery will take three years, allowing for extensive progress in design of the rest of the instrument in the interim. Applications will focus on petroleomics, top-down proteomics, and hydrogen/deuterium exchange to map contact surfaces in biomacromolecular complexes.
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