Award Abstract # 0850319
Linking Text Mining with Ontology and Systems Biology

NSF Org: DBI
Division of Biological Infrastructure
Recipient: GEORGETOWN UNIVERSITY
Initial Amendment Date: September 1, 2009
Latest Amendment Date: September 1, 2009
Award Number: 0850319
Award Instrument: Standard Grant
Program Manager: Anne Maglia
DBI
 Division of Biological Infrastructure
BIO
 Directorate for Biological Sciences
Start Date: September 1, 2009
End Date: August 31, 2014 (Estimated)
Total Intended Award Amount: $150,040.00
Total Awarded Amount to Date: $150,040.00
Funds Obligated to Date: FY 2009 = $150,040.00
History of Investigator:
  • Cathy Wu (Principal Investigator)
    wuc@udel.edu
  • Michelle Giglio (Co-Principal Investigator)
Recipient Sponsored Research Office: Georgetown University
MAIN CAMPUS
WASHINGTON
DC  US  20057
(202)625-0100
Sponsor Congressional District: 00
Primary Place of Performance: Georgetown University School of Medicine
MAIN CAMPUS
WASHINGTON
DC  US  20057
Primary Place of Performance
Congressional District:
00
Unique Entity Identifier (UEI): TF2CMKY1HMX9
Parent UEI: TF2CMKY1HMX9
NSF Program(s): ADVANCES IN BIO INFORMATICS
Primary Program Source: 01000910DB NSF RESEARCH & RELATED ACTIVIT
Program Reference Code(s): 1165, 9178, 9183, 9184, BIOT
Program Element Code(s): 116500
Award Agency Code: 4900
Fund Agency Code: 4900
Assistance Listing Number(s): 47.074

ABSTRACT

Georgetown University is awarded a grant to conduct a series of BioCreative Challenge Evaluations and Biocuration Workshops to address the current barriers in using text mining tools in the biology domain. Specifically, three workshops will be organized to bring together the biological research community and developers of text mining tools for user requirement analysis, user-based evaluations and standard development for tool integration. The specific aims of the workshops are to: (i) define requirements and evaluation criteria that will maximize utilization of text mining tools by the broad biological user community; (ii) provide both system- and user-based evaluations, with metrics that measure precision and recall (system-based), as well as the effect of text mining on biocuration and knowledge discovery such as throughput and quality (user-based); and (iii) adopt, develop and recommend community standards to improve interoperability of text mining tools for data exchange and tool integration. The outcome will be to bridge the gap in linking literature to knowledge by focusing on biological use cases for database curation and knowledge discovery. The deliverables from the workshops will consist of: (i) text mining tools, including interactive and/or integrated text mining systems, that are benchmarked and evaluated by BioCreative, (ii) literature corpora used in the BioCreative evaluations, and (iii) scientific publications from these workshops in special issues of high impact journals containing results, evaluations and critical articles, including recommendations for community standards for text mining. Georgetown will collaborate with the Mitre Corporation in carrying out this workshop series.

The workshops will connect the text mining and biological communities to develop common standards and user requirements, with broad impact beyond the specific text mining applications in this project. The project will provide interdisciplinary research experience for students and researchers involved in the project or participate in the workshops. The project will provide a research and educational infrastructure for broad areas of biology, allowing text mining systems to become an enabling infrastructure for biocuration and knowledge discovery. Further information on the Biocreative workshop activities may be found at http://biocreative.sourceforge.net/

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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(Showing: 1 - 10 of 16)
Arighi CN, Carterette B, Cohen KB, Krallinger M, Wilbur WJ, Fey P, Dodson R, Cooper L, Van Slyke CE, Dahdul W, Mabee P, Li D, Harris B, Gillespie M, Jimenez S, Roberts P, Matthews L, Becker K, Drabkin H, Bello S, Licata L, Chatr-Aryamontri A, Schaeffer "An overview of the BioCreative 2012 Workshop Track III: interactive text mining task" Database , v.2013 , 2013 , p.bas056 doi: 10.1093/database/bas056
Arighi CN, Wu CH, Cohen KB, Hirschman L, Krallinger M, Valencia A, Lu Z,Wilbur JW, Wiegers TC. "BioCreative-IV virtual issue" Database , v.2014 , 2014 , p.bau039 doi: 10.1093/database/bau039
Cecilia Arighi, Phoebe Roberts, Shashank Agarwal, Sanmitra Bhattacharya, Gianni Cesareni, Andrew Chatr-aryamontri, Simon Clematide, Pascale Gaudet, Michele Gwinn Giglio, Ian Harrow, Eva Huala, Martin Krallinger, Ulf Leser, Donghui Li, Feifan Liu, Zhiyo "BioCreative III Interactive Task: an Overview" BMC Bioinformatics , v.12, S8 , 2011 , p.S4
Cecilia Arighi, Zhiyong Lu, Martin Krallinger, Kevin Cohen, W. John Wilbur, Alfonso Valencia, Lynette Hirschman and Cathy Wu "Overview of the BioCreative III Workshop" BMC Bioinformatics , v.12, S8 , 2011 , p.S1
Comeau DC, Batista-Navarro RT, Dai HJ, Do?an RI, Yepes AJ, Khare R, Lu Z, Marques H, Mattingly CJ, Neves M, Peng Y, Rak R, Rinaldi F, Tsai RT, Verspoor K, Wiegers TC, Wu CH, Wilbur WJ "BioC interoperability track overview" Database , v.2014 , 2014 , p.bau053 doi: 10.1093/database/bau053
Comeau DC, Do?an RI, Ciccarese P, Cohen KB, Krallinger M, Leitner F, Lu Z, Peng Y, Rinaldi F, Torii M, Valencia A, Verspoor K, Wiegers TC, Wu CH, Wilbur WJ "BioC: A minimalist approach to interoperability for biomedical text processing" Database , v.2013 , 2013 , p.bat064 doi: 10.1093/database/bat064
irschman L, Burns GA, Krallinger M, Arighi C, Cohen KB, Valencia A, Wu CH, Chatr-Aryamontri A, Dowell KG, Huala E, Lourenço A, Nash R, Veuthey AL, Wiegers T, Winter AG. "Text mining for the biocuration workflow" Database (Oxford) , v.2012 , 2012 , p.bas020 10.1093/database/bas020
Liu W, Islamaj Do?an R, Kwon D, Marques H, Rinaldi F, Wilbur WJ, Comeau DC "BioC implementations in Go, Perl, Python and Ruby" Database , v.2014 , 2014 , p.bau059 doi: 10.1093/database/bau059
Lu Z, Hirschman L "Biocuration workflows and text mining: overview of the BioCreative 2012 Workshop Track II" Database , v.2012 , 2012 , p.bas043 doi: 10.1093/database/bas043
Mao Y, Van Auken K, Li D, Arighi CN, McQuilton P, Hayman GT, Tweedie S, Schaeffer ML, Laulederkind SJ, Wang SJ, Gobeill J, Ruch P, Luu AT, Kim JJ, Chiang JH, Chen YD, Yang CJ, Liu H, Zhu D, Li Y, Yu H, Emadzadeh E, Gonzalez G, Chen JM, Dai HJ, Lu Z "Overview of the gene ontology task at BioCreative IV" Database , v.2014 , 2014 , p.bau086 doi:10.1093/database/bau086
Martin Krallinger, Miguel Vazquez, Florian Leitner, David Salgado, Andrew Chatr-Aryamontri, Andrew Winter, Livia Perfetto, Leonardo Briganti, Luana Licata, Marta Iannuccelli, Gianni Cesareni, Fabio Rinaldi, Robert Leaman, Graciela Gonzalez, Sergio Mato "The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text" BMC Bioinformatics , v.12, S8 , 2011 , p.S3
(Showing: 1 - 10 of 16)

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