| NSF Org: |
ECCS Division of Electrical, Communications and Cyber Systems |
| Recipient: |
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| Initial Amendment Date: | March 31, 2020 |
| Latest Amendment Date: | March 31, 2020 |
| Award Number: | 2026744 |
| Award Instrument: | Standard Grant |
| Program Manager: |
John Zhang
ECCS Division of Electrical, Communications and Cyber Systems ENG Directorate for Engineering |
| Start Date: | January 1, 2020 |
| End Date: | December 31, 2020 (Estimated) |
| Total Intended Award Amount: | $129,865.00 |
| Total Awarded Amount to Date: | $145,865.00 |
| Funds Obligated to Date: |
FY 2015 = $16,000.00 |
| History of Investigator: |
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| Recipient Sponsored Research Office: |
6100 MAIN ST Houston TX US 77005-1827 (713)348-4820 |
| Sponsor Congressional District: |
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| Primary Place of Performance: |
TX US 77005-1827 |
| Primary Place of
Performance Congressional District: |
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| Unique Entity Identifier (UEI): |
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| Parent UEI: |
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| NSF Program(s): | CCSS-Comms Circuits & Sens Sys |
| Primary Program Source: |
01001516DB NSF RESEARCH & RELATED ACTIVIT |
| Program Reference Code(s): |
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| Program Element Code(s): |
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| Award Agency Code: | 4900 |
| Fund Agency Code: | 4900 |
| Assistance Listing Number(s): | 47.041 |
ABSTRACT
The proposed research aims to develop innovative wearable, self-powered textile biosystems for in situ health monitoring and disease detection. This technology will be integrated directly onto fabrics and garments to provide lightweight, unobtrusive wearable sensing systems that do not compromise wearer mobility, comfort or attention.
Intellectual Merit: The current capabilities of wearable senosr technology are limited to measuring physiological parameters (e.g. heart rate, blood pressure, respiratory rate) and little attention has been directed toward wearable sensors for biomolecular detection. This proposed research will realize new wearable, self-powered textile biosensors offering innovative paradigms in BioMEMS, wearable sensing and point-of-care diagnostics. Textile batteries activated by body fluids for on-demand electricity generation is a fundamentally innovative concept which will provide new scientific insights into the design and operation of novel batteries based on nontraditional materials (i.e. fabric, urine, sweat).
Broad Impact: The proposed project has a broad impact and will potentially transform healthcare and improve human well-being by (1) providing an economical means for continuous health monitoring, (2) supporting preventive medicine through early disease detection, (3) reducing healthcare costs and its burden on world economies, and (4) offering low cost diagnostics suitable for use in resource-limited countries. The PI will develop new educational and outreach activities that will enhance BioMEMS research at MSU, promote STEM disciplines to K-12 students and teachers, and increase participation by women and unrepresented minority students. Activities will include: 1) Developing a new undergraduate/graduate course (ME 491: BioMEMS Sensing and Integration) that will strengthen the existing MEMS curriculum at MSU; 2) Recruiting and mentoring engineering students, particular women and underrepresented minorities, in biomedical research; and 3) Developing new outreach programs for middle/high school teachers and students to promote STEM fields to future generations of K-12 students.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
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PROJECT OUTCOMES REPORT
Disclaimer
This Project Outcomes Report for the General Public is displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed in this Report are those of the PI and do not necessarily reflect the views of the National Science Foundation; NSF has not approved or endorsed its content.
This project has provided new insights into the use of textiles and fabrics for the development of chemical sensors and batteries for point-of-care testing and wearable sensing. Key project outcomes include: (1) flexible, lightweight textile batteries activated by small volumes (10's of microliters) of liquid, which can generate 1.3 V per cell; (2) a novel technique for fabricating embroidered electrodes on textiles and garments, which can withstand repeated (100's of cycles) mechanical deformation and large stretching forces (>10 N) without experiencing damage or loss in sensor performance; (3) electrochemical sensor coatings containing conductive nanoparticles for enhanced biocompatibility and analytical performance; (4) methodologies for integrating fluidic, sensing and power components onto textiles, and interfacing with portable electrochemical instrumentation; (5) fundamental studies on analyte transport and electrochemical kinetics in textile electrochemical sensors and batteries; and (6) textile-based wearable sensing platforms for quantitative measurements of metabolites and enzyme biomarkers in human biofluid samples, including blood, urine and wound fluid.
Research efforts related to this grant have resulted in 9 peer-reviewed articles in scientific journals and conference proceedings, 6 oral/poster presentations at scientific meetings and conferences, 1 PhD thesis dissertation and 1 international patent. This grant has also supported the training of 3 PhD students, 6 undergraduate students and 3 middle and high school teachers, many of whom are women or from underrepresented groups. More than 130 high school students gained hands-on research experiences in microfluidics through participating in outreach activities developed from this project. This grant also supported the development of a new course on microfluidics at Michigan State University. This course was offered for the first time in Fall 2014, and subsequently in Fall 2016 and Fall 2018.
Last Modified: 04/02/2021
Modified by: Peter B Lillehoj
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