Award Abstract # 1351896
CAREER:Optical Coherence Engineering

NSF Org: ECCS
Division of Electrical, Communications and Cyber Systems
Recipient: REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE
Initial Amendment Date: May 9, 2014
Latest Amendment Date: May 9, 2014
Award Number: 1351896
Award Instrument: Standard Grant
Program Manager: Ruyan Guo
ECCS
 Division of Electrical, Communications and Cyber Systems
ENG
 Directorate for Engineering
Start Date: June 1, 2014
End Date: May 31, 2019 (Estimated)
Total Intended Award Amount: $400,000.00
Total Awarded Amount to Date: $400,000.00
Funds Obligated to Date: FY 2014 = $400,000.00
History of Investigator:
  • Laura Waller (Principal Investigator)
    waller@berkeley.edu
Recipient Sponsored Research Office: University of California-Berkeley
1608 4TH ST STE 201
BERKELEY
CA  US  94710-1749
(510)643-3891
Sponsor Congressional District: 12
Primary Place of Performance: University of California-Berkeley
2150 Shattuck Ave, St. 313
Berkeley
CA  US  94704-5940
Primary Place of Performance
Congressional District:
12
Unique Entity Identifier (UEI): GS3YEVSS12N6
Parent UEI:
NSF Program(s): EPMD-ElectrnPhoton&MagnDevices
Primary Program Source: 01001415DB NSF RESEARCH & RELATED ACTIVIT
Program Reference Code(s): 094E, 1045
Program Element Code(s): 151700
Award Agency Code: 4900
Fund Agency Code: 4900
Assistance Listing Number(s): 47.041

ABSTRACT

Most light that people observe (e.g. light bulbs, sun light) is only partially coherent, whereas light from a laser is coherent. This project aims to design and build optical systems for imaging partially coherent light. If successful, this research will lead to novel cameras with the ability to digitally refocus and remove aberrations in images. It would also make possible to synthetically propagate light through any optical system (e.g. a microscope or camera) and replace many optical elements via computation. The knowledge developed by this work will lead to new imaging techniques for commercial products and research instrumentation tools. Research results from this project will be used to teach optics and coherence theory to a broad audience through a collection of demos that will be disseminated at outreach events and on popular websites. The long-term educational goals of the PI include promoting hands-on science experience to the next generation of scientists and engineers.


The objective of this research is to build experimental and computational schemes for imaging four-dimensional (4D) partially spatially coherent light. The approach is to use computational imaging, whereby hardware and post-processing algorithms are designed simultaneously within the framework of phase space optics. Smart coding strategies will be developed for imaging systems based on spatial light modulators, in order to enable fast capture of high-resolution coherence information in 4D. Since partially coherent light beams have many more degrees-of-freedom, there is an opportunity for encoding and decoding greater amounts of information. This will lead to the ability to digitally focus images taken with lens-less cameras, digitally remove aberrations, and digitally filter images to extract new information in post-processing. This project will benefit scientific discovery by providing simple imaging systems for visualizing coherence, an invisible quantity of fundamental importance in optical sciences.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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H. Liu, J. Zhong, L. Waller "Multiplexed phase-space imaging for 3D fluorescence microscopy" Optics Express , v.25 , 2017 , p.14986
J. Zhang, N. Pegard, J. Zhong, H. Adesnik, L. Waller "3D computer-generated holography by nonconvex optimization" Optica , v.4 , 2017 , p.1306
L. Tian, L. Waller "3D intensity and phase imaging from light field measurements in an LED array microscope" Optica , v.2 , 2015 , p.104
L. Waller "3D imaging through scattering with light field datasets" SPIE BIOS: High-speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management conference, February 2016, San Francisco, CA. *Invited , v.paper 9 , 2016
M. Chen, L. Tian, L. Waller "3D Differential phase contrast microscopy" Biomedical Optics Express , v.7 , 2016 , p.3940
N. Antipa, G. Kuo, R. Heckel, E. Bostan, B. Mildenhall, R. Ng, L. Waller "DiffuserCam: lensless single-exposure 3D imaging" Optica , v.5 , 2018 , p.1
N. Antipa, P. Oare, E. Bostan, L. Waller, "?Video from Stills: Lensless imaging with rolling shutter,?" International Conference on Computational Photography talk , 2019
N. Antipa, S. Necula, R. Ng, L. Waller, "Single-shot diffuser-encoded light field imaging" International Conference on Computational Photography *Best Paper Award , v.Paper 7 , 2016
N. Pegard, H. Liu, N. Antipa, L. Waller, H. Adesnik "Functional brain imaging at cellular resolution with compressive light-field microscopy" OSA Computational Optical Sensing and Imaging conference, June 2015, Arlington, VA. , v.paper J , 2015
Tian, Lei and Waller, Laura "3D intensity and phase imaging from light field measurements in an LED array microscope" Optica , v.2 , 2015 , p.104 http://www.opticsinfobase.org/optica/abstract.cfm?URI=optica-2-2-104

PROJECT OUTCOMES REPORT

Disclaimer

This Project Outcomes Report for the General Public is displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed in this Report are those of the PI and do not necessarily reflect the views of the National Science Foundation; NSF has not approved or endorsed its content.

This project aimed to develop high-dimensional imaging techniques for measuring optical spatial coherence properties in four dimensions (4D). Spatial coherence is a fundamental property of light and its measurement is required for predicting behavior of light through an optical system. Measurements in 3D can be used for digital refocusing, 3D imaging, removal of scattering effects and digital correction of image aberrations.

Most light, other than laser light, is spatially partially coherent (e.g. light bulbs, LEDs), leading to complicated behavior upon propagation and optical manipulation in imaging systems. Where coherence properties can be measured, a complete description of the light can be obtained, which may enable computational correction of imaging systems. In this project, we designed methods for efficient and practical 4D spatial coherenc measurements using custom-built optical systems. 

We developed coded apertures and computational inverse problems in order to achieve high-resolution imaging of 4D coherence properties. We co-designed the optical hardware and software algorithms for efficient and fast imaging. Experimental and theoretical demonstrations were used to verify our methods on known and unknown sample objects.

The broader impacts of this project include new tools for biological microscopy, physics and new knowledge about the coherence properties of light. We are working to implement our methods in standard biological labs for routine microscopy experiments with new types of information available to be imaged. Educational goals taught and promoted optics in classrooms and for the general public relating to the basic properties of light, including coherence.

 


Last Modified: 08/10/2019
Modified by: Laura Waller

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