Award Abstract # 0700659
Nanoengineered, Manufacturable, Ion-Implantation Seeded Silica Nanowires for Sensitive BioScreening

NSF Org: CMMI
Division of Civil, Mechanical, and Manufacturing Innovation
Recipient: UNIVERSITY OF SOUTH FLORIDA
Initial Amendment Date: May 1, 2007
Latest Amendment Date: August 22, 2011
Award Number: 0700659
Award Instrument: Standard Grant
Program Manager: Glaucio H. Paulino
CMMI
 Division of Civil, Mechanical, and Manufacturing Innovation
ENG
 Directorate for Engineering
Start Date: May 1, 2007
End Date: February 29, 2012 (Estimated)
Total Intended Award Amount: $0.00
Total Awarded Amount to Date: $425,450.00
Funds Obligated to Date: FY 2007 = $289,980.00
FY 2008 = $29,220.00

FY 2009 = $21,750.00

FY 2010 = $11,169.00

FY 2011 = $0.00
History of Investigator:
  • Shekhar Bhansali (Principal Investigator)
    shekhar.bhansali@gmail.com
  • Qiang Huang (Co-Principal Investigator)
Recipient Sponsored Research Office: University of South Florida
4202 E FOWLER AVE
TAMPA
FL  US  33620-5800
(813)974-2897
Sponsor Congressional District: 15
Primary Place of Performance: University of South Florida
4202 E FOWLER AVE
TAMPA
FL  US  33620-5800
Primary Place of Performance
Congressional District:
15
Unique Entity Identifier (UEI): NKAZLXLL7Z91
Parent UEI:
NSF Program(s): NANOMANUFACTURING,
EDA-Eng Diversity Activities
Primary Program Source: 01000910DB NSF RESEARCH & RELATED ACTIVIT
01000809DB NSF RESEARCH & RELATED ACTIVIT

01001011DB NSF RESEARCH & RELATED ACTIVIT

app-0107 

01001112DB NSF RESEARCH & RELATED ACTIVIT
Program Reference Code(s): 7680, 7974, 7218, 9231, 7233, 9179, 115E, 9178, 9251, 9146, 116E, 084E, 1788, 083E, MANU, 082E
Program Element Code(s): 178800, 768000
Award Agency Code: 4900
Fund Agency Code: 4900
Assistance Listing Number(s): 47.041

ABSTRACT

The goal of this research is to develop a cost effective, robust, reproducible, stable SERS (Surface Enhanced Raman Spectroscopy) substrate with high spatial resolution for ultra-sensitive biodiagnostics. SERS is a powerful, versatile bioscreening technique based on molecular vibrations that currently lacks a tunable, homogenous, repeatable, inexpensive and sensitive substrate of uniform geometry. The central focus of this research is to address the existing SERS challenge through the development of a robust, mass manufacturable, ultra dense, reproducible ordered array of ion implantation seeded silica nanowires of well defined geometry as an effective SERS substrate.

The research objectives of the proposal are to (a) investigate and study the growth kinetics of ion-implantation seeded selective nucleation of silica nanowires, (b) synthesize ultra-dense massively parallel array of vertically aligned wires of controlled geometry, (c) develop and apply robust, dynamic nanomanufacturing schemes to achieve reliable and reproducible fabrication of these batch fabricated nanowires, (d) validate the spatially confined SERS substrate for active bioscreening by real-time detection of the desired species and (e) develop a strong interdisciplinary, laboratory-based research, education and outreach program focusing on integration of biology, nanomanufacturing, and microsystems that will have an impact on the training of middle school, high school, community college students and teaching fraternity from all backgrounds.
Intellectual Merit: The research opens the gateway for using ion implantation as a general purpose nanoscale catalysis tool towards mass manufacturing bottom-up controlled nanosystems for wide variety of applications.
Broader Impact: Advancements in the field of nanoscale science, tools and techniques with emphasis on emerging disciplines like nanomanufacturing would be widely disseminated through the innovative "K- PhD" program. Moreover, the research has participation of the underrepresented groups (minority, women) and fosters partnerships through ongoing international collaboration and exchange. The results of the research will translate into case studies in course modules and seminars/presentations rendered by the investigators.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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(Showing: 1 - 10 of 11)
Qiang Huang, Li Wang, Tirthankar Dasgupta, Li Zhu, Praveen K. Sekhar, Shekhar Bhansali, Yu An, and Daniel J. Epstein "Statistical Weight Kinetics Modeling and Estimation for Silica Nanowire Growth Catalyzed by Pd Thin Film" IEEE Automation Science and Engineering , 2010
Eduardo Murphy-Perez, Sunil K. Arya, and Shekhar Bhansali "Vaporâ??liquidâ??solid grown silica nanowire based electrochemical glucose" Analyst , v.8 , 2011 , p.1686 10.1039/C0AN00977F
M-S.Kim, P.K.Sekhar, S.Bhansali and J.P. Harmon "Dielectric Properties of Novel Polyurethane/Silica Nanowire Composites" Journal of Nanoscience and Nanotechnology , v.9 , 2009 , p.1
M-S.Kim, P.K.Sekhar, S.Bhansali and J.P. Harmon "Spectrum Analysis of Dielectric Properties of Novel PU Composites using Silica Nanowires" Nanotechnology , 2009 , p.5776
P.K.Sekhar and S.Bhansali "Manufacturing Aspects of Oxide Nanowire" Materials Letters , v.64 , 2010 , p.729
P.K. Sekhar, N.S. Ramgir, R.K.Joshi and S. Bhansali "Selective Growth of Silica Nanowires using Au Catalyst for Optical Recognition of Interleukin-10" Nanotechnology , v.19 , 2008 , p.245502
P.K.Sekhar, R.G.Elliman, A.R. Wilkinson, and S. Bhansali "Enriched Er Emission from Nanoengineered Si Surface" The Journal of Physical Chemistry C: Letters , v.112 , 2008 , p.20109
Ramgir, NS; Zajac, A; Sekhar, PK; Lee, L; Zhukov, TA; Bhansali, S "Voltammetric detection of cancer biomarkers exemplified by interleukin-10 and osteopontin with silica nanowires" JOURNAL OF PHYSICAL CHEMISTRY C , v.111 , 2007 , p.13981 View record at Web of Science 10.1021/jp073371
R.G. Elliman, A.R. Wilkinson, P.K.Sekhar and S. Bhansali "Optical emission from erbium-doped silica nanowires" Journal of Applied Physics , v.103 , 2008 , p.104304
Sekhar, PK; Bhansali, S "Manufacturing aspects of oxide nanowires" MATERIALS LETTERS , v.64 , 2010 , p.729 View record at Web of Science 10.1016/j.matlet.2009.12.05
Sekhar, PK; Ramgir, NS; Bhansali, S "Metal-decorated silica nanowires: An active surface-enhanced Raman substrate for cancer biomarker detection" JOURNAL OF PHYSICAL CHEMISTRY C , v.112 , 2008 , p.1729 View record at Web of Science 10.1021/jp077698
(Showing: 1 - 10 of 11)

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