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News From the Field

Engineering 'hairpins' increases CRISPR accuracy


April 15, 2019

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Biomedical engineers at Duke University have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. The approach adds a short tail to the guide RNA that folds back and binds onto itself, creating a "lock" that can only be undone by the targeted DNA sequence. Full Story

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Duke University

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