News From the Field
Engineering 'hairpins' increases CRISPR accuracy
April 15, 2019
This material is available primarily for archival purposes. Telephone numbers or other contact information may be out of date; please see current contact information at media contacts.Biomedical engineers at Duke University have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. The approach adds a short tail to the guide RNA that folds back and binds onto itself, creating a "lock" that can only be undone by the targeted DNA sequence. Full Story
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