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CRISPR scissors, Cas12a, enables cutting-edge diagnostics


February 15, 2018

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Utilizing an unsuspected activity of the CRISPR-Cas12a protein, University of California, Berkeley, researchers created a simple diagnostic system called DETECTR to analyze cells, blood, saliva, urine and stool to detect genetic mutations, cancer and antibiotic resistance and also diagnose bacterial and viral infections. The scientists discovered that when Cas12a binds its double-stranded DNA target, it indiscriminately chews up all single-stranded DNA.Full Story

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University of California, Berkeley

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