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Key factor identified in gene silencing


August 30, 2017

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In a paper published this week in Proceedings of the National Academy of Sciences, Hengbin Wang and colleagues describe a key role for a protein called RSF1 in silencing genes. Besides the molecular biology details, the researchers also showed that disruption of RSF1 expression in the embryos of African clawed frogs caused severe developmental defects in the tadpoles--through a dysregulation of mesodermal cell fate specification.Full Story

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University of Alabama at Birmingham

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