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Gene responsible for hereditary cancer syndrome found to disrupt critical growth-regulating pathway


November 7, 2013

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Whitehead Institute scientists have reported that the gene mutated in the rare hereditary disorder known as Birt-Hogg- Dubé cancer syndrome prevents activation of mTORC1, a critical nutrient-sensing and growth-regulating cellular pathway. This is an unexpected finding, as some cancers keep this pathway turned on to fuel their unchecked growth and expansion. Full Story

Source
Whitehead Institute for Biomedical Research

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