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News Release 05-073

Little Microbe Inside Sea Squirt Makes Big Splash

Bacterial genome sheds light on synthesizing cancer-fighting compounds

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Patellamide production in bacterium

Scientists discovered Prochloron didemnii has the necessary genes to produce patellamides, compounds that may one day be used in cancer treatment. They were also able to transfer the patellamide genes to the laboratory workhorse bacterium, Escherichia coli, directing it to biosynthesize the product.

Credit: Nicolle Rager Fuller, National Science Foundation


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a sea squirt

Sea squirts, like the one shown above, contain a microbe that produces potential cancer-fighting chemicals.

Credit: Adriaan Gittenberger (www.ascidians.com)


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