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Division of Chemistry

Molecular Foundations for Biotechnology  (MFB)

Name Email Phone Room
Tingyu  Li (703) 292-4949   
Herman  O. Sintim (703) 292-7244   
Kelsey  D. Cook (703) 292-7490   


Solicitation  21-540

Important Information for Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 20-1), is effective for proposals submitted, or due, on or after June 1, 2020. Please be advised that, depending on the specified due date, the guidelines contained in NSF 20-1 may apply to proposals submitted in response to this funding opportunity.


This initiative calls for fundamentally new approaches in chemistry to drive new directions in biotechnology, an important Industry of the Future (IotF). Collaborative high risk/high reward projects are sought; the research must involve innovative chemistry.

A multi-year campaign is envisioned (contingent on availability of funding), targeting broad annual themes. This year’s solicitation calls for synergistic scientific partnerships grounded in the principles of synthetic, physical organic and molecular recognition chemistry creating novel chemical biology tools to drive innovations in biotechnology.  The focus is on the development and deployment of fundamentally new techniques to modify the structure, function and/or fate of proteins interacting with small molecules for important applications in biotechnology.

What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)

Map of Recent Awards Made Through This Program