Genetic Mechanisms

Name Email Phone Room
Manju  Hingorani 703-292-7323  E12469  
Stephen  DiFazio (703) 292-4517  E12472  
Candi Phoebe  Lostroh (703) 292-7145  E12474  
Arcady  R. Mushegian (703) 292-8528  E 12475  


Apply to NSF 21-509

The cluster supports inventive research to address fundamental mechanisms involved in the organization, dynamics, processing, expression, regulation, and evolution of genetic and epigenetic information. Cross-disciplinary and collaborative research is encouraged, especially when perspectives and quantitative approaches from computational, mathematical, chemical and physical sciences, and engineering are used.  Development of creative technological solutions is also welcome, when driven by the potential to produce significant new knowledge about genetic mechanisms. Projects that are primarily descriptive are given lower priority.

Proposals in the following areas are of particular interest:

  • Principles governing the spatiotemporal organization and coordination of processes that maintain, replicate, transcribe, and translate genomic information.
  • Predictive studies of the relationship of genomic and epigenomic determinants to molecular- or cellular-scale phenotypes.
  • Investigations of the evolutionary origins and functions of genes and genomes.

The following NSF priorities might be of interest to the Genetic Mechanisms community:

  • NSF Big Ideas: Understanding Rules of Life, Navigating the New Arctic, and NSF INCLUDES.
  • Industries of the Future: Biotechnology/Bioeconomy, Artificial Intelligence, and Advanced Manufacturing.

Investigators are welcome to contact GM program directors for further information.