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Integrative Organismal Systems (IOS)
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Integrative Organismal Systems (IOS)

IOS Revised Solicitation

A revised IOS Core Programs solicitation, NSF 16-505, replaces NSF 13-600 (October 2015). The revised solicitation includes two significant programmatic changes.

1. Proposals on the interaction of plants with their microbial and invertebrate pathogens, pests and symbionts will now be accepted for review by a new program, Plant Biotic Interactions (PBI), jointly supported and managed by NSF IOS and the USDA National Institute of Food and Agriculture (NIFA) instead of being considered by the Symbiosis, Defense and Self-recognition (SDS) program. The anticipated submission deadline for full proposals to the new PBI Program will be in April 2016. The PBI program will not require submission of preliminary proposals in its review process. Complete information about this new joint NSF/NIFA program will be forthcoming in late 2015.

Proposals in the area of plant-biotic interactions should no longer be submitted through the IOS Core Programs solicitation to the SDS program.

There is no change in the review of proposals on the interaction of animal hosts with their pathogens, pests and symbionts, organelle acquisition, or symbioses among and between prokaryotes and protists. Proposals on these topics should continue to be submitted to the SDS program via the IOS Core Programs solicitation.

Proposals focused on development of functional genomic tools, approaches and associated infrastructure aimed at enabling genome manipulation in plant symbioses may be submitted to the new Enabling Discovery through Genomic Tools (EDGE) track of the revised IOS Core Programs solicitation (see below).

The description of the SDS Program has been updated to accommodate the changes regarding plant symbioses, and plant self/non-self recognition (see the Physiological and Structural Systems Webpage).

2. The revised IOS Core Programs solicitation includes two tracks for proposal submission. The Core track remains essentially unchanged from the description in the previous IOS solicitation (NSF 13-600), except for the changes noted above for the SDS Program. The Core track continues to encompass a two-phase merit review process, with submission of full proposals by invitation only, after merit review of preliminary proposals, which are required. An annual limit of two preliminary proposal submissions by PIs and co-PIs remains in effect for the Core track.

The EDGE (Enabling Discovery through Genomic Tools )track is designed for research addressing current impediments to progress in understanding a range of important questions in organismal biology and in particular the understanding of the genomes-to-phenomes relationship. EDGE projects should focus on development of functional genomic tools, approaches and associated infrastructure to enable genome manipulation in diverse, emerging model organisms. EDGE proposals must additionally include training and rapid dissemination plans enabling larger communities of investigators to utilize the newly developed tools, thereby catalyzing an increase in the capacity of research communities to test cause-and-effect hypotheses about genes and phenotypes in organisms presently lacking such tools. Proposers who wish to submit to the EDGE track must submit a Letter of Intent prior to submission of the full proposal. Proposals relevant to plant symbioses may be submitted to the EDGE track of this solicitation. There are no annual limits for PI and co-PI proposal submissions to the EDGE track.

IOS Special Announcements

NEW Frequently asked questions for the IOS core programs solicitation have just been released and can be found at http://www.nsf.gov/pubs/2016/nsf16017/nsf16017.jsp.  

NEW Dear Colleague Letter: Special Guidelines for Submitting Collaborative Proposals under the US NSF/BIO/IOS - US-Israel BSF International Opportunity. Click here for this funding opportunity.

Cracking the Olfactory Code – An Ideas Lab Activity: To advance our broader understanding of the nature of olfactory processing and sensory representations in the brain in general, the National Science Foundation (NSF) has awarded more than $15 million for three projects to research the intricacies of olfaction. For more information about the awards click here.

Frontiers for the Integrative Study of Animal Behavior. - See the Workshop report for further details.

Grand Challenges in Organismal Biology: How Organisms Walk the Tightrope Between Stability and Change - See the Workshop report for further details.

Find more IOS news on our blog, IOS in Focus. Follow us at http://nsfiosinfocus.wordpress.com.

If you're a new visitor to the Directorate for Biological Sciences website or just want a quick visual and textual summary of our areas of support, please visit the "About BIO" web page where we have added a new interactive organization chart.

See "Additional BIO Resources" for other items of interest including BIO's Guidance on Data Management Plans and BIO Dear Colleague Letters.

BIO Program Director and Reviewer Opportunities

NOTE: March 1 annually (or next business day if that is a weekend or holiday) is the target date for most IOS programs for REU, RET, RAHSS, and ROA supplements as well as proposals for Conferences, Symposia and Workshops (Meetings). Guidance for IOS PIs preparing supplemental requests is posted at:  http://www.nsf.gov/bio/ios/suppopp.jsp  For Guidance on preparing Proposals for Conferences, Symposia and Workshops (Meetings) visit http://www.nsf.gov/bio/ios/confworkshopguidance.jsp

Please be sure to check the Division of Emerging Frontiers (EF) for additional grant competitions.

Programs and Funding Opportunities

Key: Crosscutting Crosscutting | NSF Wide Flag NSF-wide

Division of Integrative Organismal Systems
IOS Cluster Descriptions
bullet Behavioral Systems
bullet Developmental Systems
bullet Neural Systems
bullet Physiological and Structural Systems
Plant Genome Research Program (PGRP)
bullet Basic Research to Enable Agricultural Development  (BREAD)
bullet Developing Country Collaborations in Plant Genome Research (DCC-PGR)
bullet Postdoctoral Research Fellowships in Biology
Additional Funding Opportunities for the IOS Community
bullet Collaborative Research in Computational Neuroscience  (CRCNS)
bullet Data Infrastructure Building Blocks  (DIBBs)
bullet Innovation Corps Teams Program  (I-Corps Teams) NSF Wide Flag
bullet Long Term Research in Environmental Biology  (LTREB)
bullet MacroSystems Biology:
bullet Ocean Acidification  (OA)
bullet Postdoctoral Research Fellowships in Biology
bullet Research Assistantships for High School Students  (RAHSS)
bullet Research Coordination Networks
bullet Research Experiences for Teachers: Supplement Opportunity  (RET)
bullet Science, Engineering and Education for Sustainability NSF-Wide Investment  (SEES) NSF Wide Flag Crosscutting
bullet Science, Technology, and Society  (STS)
Current Activities: no longer receiving proposals - IOS
bullet Cracking the Olfactory Code  (Olfactory) Crosscutting
bullet International Collaborations in Organismal Biology Between US and Israeli Investigators  (ICOB)
bullet Metabolomics for a Low Carbon Society  (METABOLOMICS)
bullet Surpassing Evolution: Transformative Approaches to Enhance the Efficiency of Photosynthesis

Featured NSF-wide Programs

Faculty Early Career Development Program NSF Wide Flag

International Research Fellowship Program NSF Wide Flag

Facilitating Research at Primarily Undergraduate Institutions: NSF Wide Flag

View All NSF-wide Programs

NSF Educational Opportunities by Audience

For Undergraduate Students

For Graduate Students

For Postdoctoral Fellows

For K-12 Educators

Upcoming Due Dates See All

National Science Foundation Research Traineeship (NRT) Program
(NSF  16-503) Letter of Intent: December 9, 2015, Applies to both tracks

EPSCoR Research Infrastructure Improvement Program: Track-2 Focused EPSCoR Collaborations (RII Track-2 FEC)
(NSF  16-511) Letter of Intent: January 11, 2016

Industry/University Cooperative Research Centers Program
(NSF  16-504) Full Proposal: January 11, 2016

Major Research Instrumentation Program:
(NSF  15-504) Full Proposal: January 13, 2016

Division of Integrative Organismal Systems

(NSF  16-505) Preliminary Proposal: January 15, 2016, Core Track

News See All

baby with a quizzical, contemplative expression Babies have logical reasoning before age one, study finds
Released November 18, 2015
News From the Field
a female hamster displays aggressive behavior IU study: Short winter days trigger aggression hormones differently based on sex
Released November 18, 2015
News From the Field
the jellyfish Aurelia aurita (moon jelly) Researchers sequence genomes of parasite that is actually a 'micro jellyfish'
Released November 16, 2015
News From the Field

Discoveries See All

Neurons of a mouse brain Video series: New strategies address one of science's greatest mysteries
36 NSF-funded research teams work to help reveal how neurons team up to produce thoughts and actions
Released  September 23, 2015

animation showing Motyxia bistipita emitting a blue green light. Shedding light on millipede evolution
A Virginia Tech entomologist discusses millipedes that light up, and some really bright ideas inspired by bioluminescence
Released  July 31, 2015

A female anopheles mosquito Breaking the cycle of malaria transmission
Discovery of protein could lead to treatment that creates 'dead end' for malaria parasite
Released  July 23, 2015

Events Calendar See All

September 10, 2015  - January 21, 2016
ADVANCE IT and IT-Catalyst pre-proposal Technical Assistance Webinars

November 9, 2015  - December 9, 2016
2016 NRT Informational Webinars

December 2, 2015  - December 3, 2015
EHR Advisory Committee Fall 2015 Meeting
Advisory Committee Meeting

December 3, 2015  - December 4, 2015
Advanced Technological Education (ATE) Program Panel

December 4, 2015
EHR Research on Early Childhood Education Open House

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