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NSF PR 03-142 - December 10, 2003

Note About Images

 

Image 1

flow Chart depicting process followed to derive sperm cell precursors

The flow chart depicts the process that George Daley, Niels Geijsen and their colleagues followed to derive sperm-like cells, and eventually culture embryoid bodies, from embryonic mouse stem cells.
Credit: Niels Geijsen, Massachusetts General Hospital / National Science Foundation
TIFF of Photo 1 (79KB)

 

Image 2

mouse embryonic stem cells

Mouse embryonic stem cells stained with a fluorescent green marker for embryonic germ cells (precursor sex cells).
Credit: Niels Geijsen, Massachusetts General Hospital/National Science Foundation
TIFF of Photo 2 (126KB)

 

Image 3

an embryoid body

An embryoid body, a globular cell cluster that the researchers cultured from mouse embryonic stem cells.
Credit: Niels Geijsen, Massachusetts General Hospital/National Science Foundation
TIFF of Photo 3 (111KB)

 

Image 4

ALT TEXT

Image depicting in vitro fertilization of an egg in a process similar to the one researchers used to fertilize mouse embryos with the sperm-like cells.
Credit: Niels Geijsen, Massachusetts General Hospital/National Science Foundation
TIFF of Photo 5 (223KB)

 

Image 5

ALT TEXT

Embryoid bodies contain cells that differentiate into mature, male, sex cells similar to sperm, but without tails. When the researchers isolated those cells and injected them directly into mouse egg cells, the eggs essentially became fertilized, and an entirely new line of early-stage mouse embryos began to grow. such an embryo is shown in this image.
Credit: Niels Geijsen, Massachusetts General Hospital/National Science Foundation
TIFF of Photo 6 (1.01MB)

 

Image 6

ALT TEXT

George Daley (left) of Children's Hospital and the Dana Farber Cancer Institute in Boston and Niels Geijsen of Massachusetts General Hospital, also in Boston.
Credit: Javier Amador-Peña, Children's Hospital Boston/National Science Foundation

 

 
 
     
 

 
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