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News From the Field
Gene responsible for hereditary cancer syndrome found to disrupt critical growth-regulating pathway

November 7, 2013

the gene FLCN Whitehead Institute scientists have reported that the gene mutated in the rare hereditary disorder known as Birt-Hogg- Dubé cancer syndrome prevents activation of mTORC1, a critical nutrient-sensing and growth-regulating cellular pathway. This is an unexpected finding, as some cancers keep this pathway turned on to fuel their unchecked growth and expansion.  Full Story

Source
Whitehead Institute for Biomedical Research

The National Science Foundation (NSF) is an independent federal agency that supports fundamental research and education across all fields of science and engineering. In fiscal year (FY) 2014, its budget is $7.2 billion. NSF funds reach all 50 states through grants to nearly 2,000 colleges, universities and other institutions. Each year, NSF receives about 50,000 competitive requests for funding, and makes about 11,500 new funding awards. NSF also awards about $593 million in professional and service contracts yearly.

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