Quantitative Systems Biotechnology
This program has been archived.
Important Information for Proposers
A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 15-1), is
effective for proposals submitted, or due, on or after December 26, 2014. The PAPPG is consistent
with, and, implements the new Uniform Administrative Requirements, Cost Principles, and Audit
Requirements for Federal Awards (Uniform Guidance) (2 CFR § 200). NSF anticipates release of
the PAPPG in the Fall of 2014. Please be advised that, depending on the specified due date,
the guidelines contained in NSF 15-1 may apply to proposals submitted in response to this
As a result of recent advances in genomic and biochemical analysis, informatics, mathematics, and the engineering disciplines, it is now possible to approach an understanding of the integrated processes which translate the information contained in the genome into functioning biological entities. Systems engineering approaches will be essential for characterizing the emergence of biological phenotypes from underlying hierarchies of interactions and environmental influences. Understanding the quantitative systems behavior of cellular systems is important in its own right as well as providing a conceptual basis for biotechnological process development.
This Quantitative Systems Biotechnology solicitation seeks innovative high-risk/high-return proposals, which combine in-depth analysis of large-scale cellular biological systems, or their representations, with creative software tools for the development of computer models as well as complementary quantitative experimental approaches. Multidisciplinary proposals are encouraged.