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Quantitative Systems Biotechnology  (QSB)  Crosscutting Programs

This program has been archived.


Name Dir/Div Name Dir/Div
Mitra  Basu CISE/CCF  Maria  K. Burka  
Ken  P. Chong   Frederick  G. Heineken  
Glenn  H. Larsen ENG/IIP  Michael  Steuerwalt MPS/DMS 
Paul  J. Werbos     


Solicitation  04-516

Important Information for Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 16-1), is effective for proposals submitted, or due, on or after January 25, 2016. Please be advised that, depending on the specified due date, the guidelines contained in NSF 16-1 may apply to proposals submitted in response to this funding opportunity.




As a result of recent advances in genomic and biochemical analysis, informatics, mathematics, and the engineering disciplines, it is now possible to approach an understanding of the integrated processes which translate the information contained in the genome into functioning biological entities.  Systems engineering approaches will be essential for characterizing the emergence of biological phenotypes from underlying hierarchies of interactions and environmental influences.  Understanding the quantitative systems behavior of cellular systems is important in its own right as well as providing a conceptual basis for biotechnological process development.

This Quantitative Systems Biotechnology solicitation seeks innovative high-risk/high-return proposals, which combine in-depth analysis of large-scale cellular biological systems, or their representations, with creative software tools for the development of computer models as well as complementary quantitative experimental approaches.  Multidisciplinary proposals are encouraged.    

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