Biomolecular Dynamics, Structure and Function

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PROGRAM GUIDELINES

PD 04-1144

Important Notice to Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG), NSF 13-1, was issued on October 4, 2012 and is effective for proposals submitted, or due, on or after January 14, 2013. Please be advised that, depending on the specified due date, the guidelines contained in NSF 13-1 may apply to proposals submitted in response to this funding opportunity.

Please be aware that significant changes have been made to the PAPPG to implement revised merit review criteria based on the National Science Board (NSB) report, National Science Foundation's Merit Review Criteria: Review and Revisions. While the two merit review criteria remain unchanged (Intellectual Merit and Broader Impacts), guidance has been provided to clarify and improve the function of the criteria. Changes will affect the project summary and project description sections of proposals. Annual and final reports also will be affected.

A by-chapter summary of this and other significant changes is provided at the beginning of both the Grant Proposal Guide and the Award & Administration Guide.

DUE DATES

Archived

SYNOPSIS

The Biomolecular Systems Cluster, one of three thematic areas within the Division of Molecular and Cellular Biosciences, supports fundamental research in the areas of molecular biophysics, molecular biochemistry, and metabolic biochemistry. The cluster emphasizes the relationships between structure, function, and dynamics in studies of individual macromolecules, macromolecular complexes, and metabolic pathways. Research of interest to the cluster includes novel and creative projects addressing protein folding and dynamics, natively unfolded proteins, protein design, molecular recognition, enzymology, energy transformations in living systems, and the components, architecture and flux in metabolic pathways.  The cluster encourages research projects integrating theoretical, computational, and experimental approaches to discover and define basic molecular mechanisms, as well as projects developing cutting-edge technologies in the context of biological questions relevant to the cluster. The cluster also encourages multi-disciplinary research at the interface of biology with physics, chemistry, mathematics, computer science, and engineering.

Program Directors:

Kamal Shukla. Molecular biophysics; computational biology, NMR and spectroscopy.

Robert L. Burnap.  Metabolic biochemistry in bacteria and plants, protein structure-function, photosynthesis.

David Rockcliffe.  Molecular biochemistry; enzymology.

What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)

Map of Recent Awards Made Through This Program

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