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Discovery
Air Shield Keeps Bacteria Out of Open Wounds

The Nimbic Systems' Air Barrier System uses proprietary technology to create a "cocoon" of highly pure air that surrounds surgical incisions

A 3-D rendering of the Air Barrier System area of protection.

A 3-D rendering of the Air Barrier System area of protection.
Credit and Larger Version

October 7, 2011

This spring, Nimbic Systems, based near Houston, Texas, received Food and Drug Administration (FDA) clearance for the company's Air Barrier System, a unique medical device for reducing surgical-incision site contamination by infection-causing microorganisms.

The Air Barrier System, or ABS, creates a "cocoon" of highly pure air that surrounds a surgical incision site. The cocoon isolates the incision from ambient air to prevent the bacteria present in the operating room from infecting the patient.

During surgery, bacteria are continuously shed by operating room personnel into the air and can subsequently settle in and around an incision site. The organisms, such as Staphylococcus aureus, are a major cause of infections in prosthesis implant surgeries such as hip and knee replacements.

The ABS device

The portable ABS device prevents contamination without disrupting the surgical procedure or impeding access to the incision area, making the device relatively easy to use.

The ABS consists of two components: A non-sterile, reusable blower unit that provides the source of HEPA filtered air, and a sterile, disposable nozzle that is affixed onto the surgical drape adjacent to the incision.

In 2009, Nimbic Systems received funding from the National Science Foundation (NSF) to conduct ABS pilot trials, with the goal of determining the degree to which localized, directed HEPA air flow generated by the ABS reduced the amount of airborne particulates and colony-forming bacteria in the surgical field during total hip arthroplasty.

Surgical intervention

Orthopedic joint arthroplasty, spinal procedures, thoracic and vascular procedures, and other long-duration procedures are high-risk for infection. Not only is the risk of harm to the patient a concern, but costs from the infections can reach up to $100,000.

The results of the preliminary hip arthroplasty trial revealed that the ABS reduces the presence of microorganisms at the incision site by greater than 84 percent.

Based on the data obtained in the pilot trials, the FDA approved the ABS for use in hip arthroplasty procedures, while future trials planned for later this year will investigate spine and femoral popliteal procedures.

-- Kylie Witherel, Nimbic Systems, k.witherel@nimbicsystems.com

This Behind the Scenes article was provided to LiveScience in partnership with the National Science Foundation.

Related Institutions/Organizations
Nimbic Systems, LLC

Locations
Texas

Related Programs
Small Business Innovation Research & Small Business Technology Transfer (Program Description)

Related Awards
#0912403 SBIR Phase I: Air Barrier System to reduce contamination of wounds during surgery

Total Grants
$99,879

Related Agencies
Food and Drug Administration

Related Websites
Air Shield Keeps Bacteria Out of Open Wounds: http://www.livescience.com/16329-nimbic-air-barrier-nsf-bts.html
Air Barrier System, Nimbic Systems: http://nimbicsystems.com/abs.html

Image of water vapor, smoke, delivered onto simulated surgery area that is being cleared by ABS.
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This short video depicts the Air Barrier System's protective "cocoon" effect.
Credit and Larger Version

Image of the Air Barrier System deployed on the sterile field just prior to incision.
The Air Barrier System nozzle is deployed on the sterile field just prior to incision.
Credit and Larger Version

Petri dishes showing how bacterial colonies are reduced by the Air Barrier System.
Number and size of bacterial colonies that grow on a nutrient rich broth are reduced by ABS.
Credit and Larger Version



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